Use as Directed
*Among OTC medicine for migraines.
IQVIA, Inc., 2018

EXCEDRIN®
MIGRAINE

The #1 Neurologist Recommended OTC migraine treatment approved by the FDA for migraine relief.*

Use as Directed
*Among OTC medicine for migraines.
IQVIA, Inc., 2018
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Excedrin® Migraine is a doctor-recommended safe and effective OTC migraine treatment. In clinical studies, patients with moderate to severe migraines experienced effective relief with just one dose.

Excedrin® Migraine contains acetaminophen, aspirin, and therapeutically active caffeine.

USES

Treats migraines3

Excedrin Migraineis the #1 neurologist-recommended OTC (over-the-counter) migraine treatment*

Approved by the FDA for migraine relief1

In clinical studies, patients with moderate to severe migraines experienced effective relief with just one dose2

*Among OTC medicine for migraines. IQVIA, Inc., 2018

DIRECTIONS

Do not take more of this product than directed

Dosage for adults: take two caplets or geltabs with a glass of water

Do not take more than two tablets in any 24-hour period, unless directed by a doctor

If you are under 18 years of age, ask a doctor before use

If symptoms persist or worsen, consult your doctor

ACTIVE INGREDIENTS

Acetaminophen:
250 mg/caplet or geltab

Aspirin(NSAID*):
250 mg/caplet or geltab

Caffeine:
65 mg/caplet or geltab

*Nonsteroidal anti-inflammatory drug

SEE FULL PRODUCT INFORMATION >

USES

Treats migraines3

Excedrin Migraineis the #1 neurologist-recommended OTC (over-the-counter) migraine treatment*

Approved by the FDA for migraine relief1

In clinical studies, patients with moderate to severe migraines experienced effective relief with just one dose2

*Among OTC medicine for migraines. IQVIA, Inc., 2018

DIRECTIONS

Do not take more of this product than directed

Dosage for adults: take two caplets or geltabs with a glass of water

Do not take more than two tablets in any 24-hour period, unless directed by a doctor

If you are under 18 years of age, ask a doctor before use

If symptoms persist or worsen, consult your doctor

ACTIVE INGREDIENTS

Acetaminophen:
250 mg/caplet or geltab

Aspirin(NSAID*):
250 mg/caplet or geltab

Caffeine:
65 mg/caplet or geltab

*Nonsteroidal anti-inflammatory drug

SEE FULL PRODUCT INFORMATION >

WARNINGS: FOR SAFE AT-HOME MIGRAINE TREATMENT

As with all medicines, Excedrin Migraine is not suitable for everyone and carries the risk of side effects – some of them serious. Please click here for the full product information, and be sure to read it through carefully before taking Excedrin Migraine.

EXCEDRIN MIGRAINE MEDICATION FAQs

CAN I TAKE OTHER MIGRAINE MEDICINE WITH EXCEDRIN MIGRAINE?

You should ask your doctor or pharmacist before taking any other drug with Excedrin Migraine. Excedrin Migraine contains an NSAID (aspirin), which may cause severe stomach bleeding. The chance is higher if you take other drugs containing prescription or nonprescription NSAIDs (aspirin, ibuprofen, naproxen, or others). You shouldn’t use Excedrin Migraine with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist.3

Medications used to relieve migraine pain typically work best when taken at first signs of a migraine–if you wait too long, the medication may not work as well.4

If you suffer from migraines that don’t respond to OTC medicine, you should talk to your doctor. They may be able to suggest a different treatment strategy.

ISN’T CAFFEINE A MIGRAINE TRIGGER? WHY IS THERE CAFFEINE IN EXCEDRIN MIGRAINE MEDICINE?

Caffeine is often cited as a migraine food trigger, but that’s not the full story. In fact, caffeine can actually help relieve headaches (including migraines) when ingested as part of an OTC headache treatment, as it boosts the effects of pain relievers like aspirin and acetaminophen–making these medicines up to 40% more effective.5 Always read and follow the product label.

Sources

1. Excedrin Migraine. Excedrin. https://www.excedrin.com/products/migraine/
Accessed 08/01/20.

2. Lipton RB, et al. Efficacy and Safety of Acetaminophen, Aspirin, and Caffeine in Alleviating Migraine Headache Pain Three Double-blind, Randomized, Placebo-Controlled Trials. Arch Neurol. 1998; 55:210-217.
Accessed 08/01/20

3. Excedrin Migraine –Drug Fact Label. National Institutes of Health. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=7ed841fb-a61c-4868-b4e5-4f2311a5e79c
Accessed 08/01/20

4. Migraine (Diagnosis & treatment). Mayo Clinic. https://www.mayoclinic.org/diseases-conditions/migraine-headache/diagnosis-treatment/drc-20360207
Accessed 08/01/20.

5. Laska JAMA 1984 251(13); 6 Apr 1711-1718 and Lipton et al. Caffeine in the management of patients with headache. The Journal of Headache and Pain (2017) 18:107
Accessed 08/01/20.

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